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Sievers Eclipse Automated Bacterial Endotoxins Testing (BET) Platform

About the Product

Experience cutting-edge efficiency and accuracy with the Sievers Automated Eclipse Bacterial Endotoxins Testing (BET) Platform. This innovative platform revolutionizes the process of endotoxin detection by reducing assay setup time by up to 85%, while significantly reducing the Limulus Amebocyte Lysate (LAL) reagent use by up to 90% with high thruput unique technology that eliminates human-driven interfering factors. The Eclipse platform optimizes your workflow by automating kinetic chromogenic assays, decreasing pipetting steps, and mitigating operator-to-operator variability. Leverage precise microfluidic liquid handling with pre-loaded calibration standards, negative & positive controls within the testing plate, and embedded endotoxin technology to maintain consistent throughput of 21 samples per plate, without the need for complex robotics.

Key Advantages

  • Complete setup for 21-sample assays in as little as 9 minutes
  • Efficient reagent usage: Reduce LAL reagent use by up to 90%
  • Compliance with global pharmacopeia regulation
  • Integrated controls: Embedded endotoxin standard curve and positive product controls (PPCs).
  • Detects endotoxins with high sensitivity, down to 0.005 EU/mL up to 50 EU/mL
  • Controls reaction temperature within 37 +/- 1 C using incubating absorbance analyzer
  • Unique centrifugation technology to assist elimination of interfering factors
  • Simplified test setup
  • Full 21 CFR Part 11 and data integrity Compliance


  • Pharmaceutical Manufacturing: Ensure drug safety and compliance by rapidly and accurately detecting endotoxins.
  • Medical Device Manufacturing: Test medical devices for bacterial endotoxins to ensure patient safety.
  • Hemodialysis Water Testing: Monitor water purity in hemodialysis, aiding in patient safety and quality control.
  • Biotechnology and Life Science Research: Accurately determine endotoxin levels in biological samples and experimental compounds.

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כנס Endotoxin & TOC

21-22 מרץ 2022

Endotoxin & TOC Conference

21-22 March 2022

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